Gold Member Since 2015
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Shanghai Yijing Industrial Co., Ltd.

Nolvadex, Clomiphene Citrate, Toremifene Citrate manufacturer / supplier in China, offering Anti-Estrogen Steroids Raloxifene Hydrochloride/Raloxifene HCl for Treating Breast Cancer 82640-04-8, Myotolon Anti-Aging Steroids Furazabols Thp Miotlo White Powder, Muscle Building Steroids Drostanolone Enanthate Anabolic Steroid Liquid 200mg/Ml and so on.

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Supplier Homepage Product Female Hormones Anti-Estrogen Steroids Raloxifene Hydrochloride/Raloxifene HCl for Treating Breast Cancer 82640-04-8

Anti-Estrogen Steroids Raloxifene Hydrochloride/Raloxifene HCl for Treating Breast Cancer 82640-04-8

Purchase Qty.:
(g)
10-19 20-29 30+
FOB Unit Price: US $3 US $2 US $1
Purchase Qty. (g) FOB Unit Price
10-19 US $3
20-29 US $2
30+ US $1
Get Latest Price
Port: Shanghai, China
Production Capacity: 100kg/Month
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: 82640-04-8
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >96%
  • Molecular Weight: 510.04
  • Average Mass: 510.0442 Da
  • Enthalpy of Vaporization: 110.08 Kj/Mol
  • Transport Package: as Your Request
  • Origin: China
  • Powder: Yes
  • Certification: ISO 9001
  • State: Solid
  • Mf: C28h28clno4s
  • Nominal Mass: 509 Da
  • Flash Point: 394.2
  • Trademark: YIJING
  • Specification: 25kg/drum
Product Description
Anti-Estrogen Steroids Raloxifene hydrochloride Powder For Treating Breast Cancer 
 
 
 

Test items
SpecificationTest results
AppearanceYellowish powderComply
IdentificationIrComply

 
It meets the requirements of the test for chorideComply
SolubilitySoluble in 10% sodium hydroxide solution, slightly soluble in methanol,insoluble in waterComply
Assay98.5%~101.5%99.15%
Related substancesRrt=0.74 impurity≤0.20%Comply

 
Other single impurity≤0.10%0.07%

 
Total impurities≤0.5%0.26%
Loss on drying≤0.5%0.10%
Residue on ignition≤0.1%Comply
Heavy metals≤10ppmComply
StoragePreserve in well-closed containers and protected from light.Store at room temperature.
ConclusionComplies with usp32 standard

Raloxifene hydrochloride Description:
Raloxifene hydrochloride is a second-generation Selective Estrogen Receptor Modulator (SERM) of the benzothiophene family. This drug is similar in effect to tamoxifen, exhibiting estrogen receptor antagonist (blocking) properties in some tissues while acting as an estrogen receptor agonist (activator) in others.
 
The main point of variation between these two agents is their tissue selectivity. While raloxifene hydrochloride is a strong anti-estrogen in breast and uterine tissues, it appears to be estrogenic in bone. This allows it to protect bone density, mimicking the beneficial effects of endogenous estradiol. This is quite different from tamoxifen, which is anti-estrogenic in both breast and bone.
 
In a role that was novel for an anti-estrogen, raloxifene hydrochloride was approved by the FDA for the prevention and treatment of osteoporosis in post-menopausal women. It is also being investigated for several other potential uses, including the treatment and prevention of cardiovascular disease, breast cancer, gynecomastia, prostate cancer, acromegaly, and uterine cancer.
 
Raloxifene hydrochloride Mechanism of Action:
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors.
 
This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism). The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors.
 
appears to act as an estrogen agonist in bone. It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence.
 
Raloxifene hydrochloride Administration:
Raloxifene hydrochloride is FDA approved for the treatment and prevention of osteoporosis in postmenopausal women, reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis, and reducing the risk of invasive breast cancer in postmenopausal women at high risk for invasive breast cancer.
 
The recommended dose is one 60 mg tablet administered once per day, without regard to meals. When used (off-label) to mitigate the estrogenic side effects of anabolic/androgenic steroid use, male athletes and bodybuilders often take 30 mg to 60 mg per day.

How do we deliver?
As for 10kg , we could use stealth packages to cover customs, subpackage is a good choice.
As for over 10kg, we could change product name to pass customs, such as DL mandelic acid, all profiles settled down.
 
How to finish the payment?
100% T/T, Moneygram, Western Union and Bitcoin. No paypal, Paypal commission charge is too high, couldn't afford it; Our products are special, easy to track our own informations through paypal, too risky for us; Once the account is frozen, it will take long time to wait it available,delivery delayed.
 
How should we do if products lost?
We have rich experience to export worldwide, excellent stealth packages and good delivery company will help.
If parcels get seized, there is perfect reship policy,no need to pay for the second time.
We will be your best supplier based on favorable quotation and good quality.
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