High Purity USP Standard Pirfenidone 53179-13-8
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|FOB Unit Price:||US $1 US $2 US $3 US $4 US $5|
|Purchase Qty. (gram)||FOB Unit Price|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: 53179-13-8
- Customized: Customized
- Suitable for: Adult
- Purity: >99%
- Assay: 99.5%
- Molecular Formula: C14h23cln2o
- Acidity pH: 4.0-5.5
- Delivery: Within 24hours After Your Payment
- Trademark: YIJING
- Specification: SGS
- HS Code: 4010320000
- Powder: Yes
- Certification: GMP, ISO 9001, USP
- State: Powder
- CAS No.: 53179-13-8
- Color: White Crystalline Powder
- Molecular Weight: 270.7982
- Payment: T/T, Western Union and Money Gram
- Express: EMS, DHL, FedEx, etc(Door-to-Door)
- Transport Package: According to Every Customers′s Requirements
- Origin: Sh
HP9012 Pirfenidone Assay: 98.5%~101.0% CAS53179-13-8 Fresh stock
|Pirfenidone||CAS 53179-13-8||Brand: Network Union|
|MW: 185.22||MSDS: Avaiable|
|MF : C12H11NO||Sample: Avaiable|
|Category:Antiinflammatory Agents||Min order: 10grams|
|Quality standard : Enterprise standard||Place of Origin:China|
|Introduction||Uses: The new anti-fibrotic material, with broad-spectrum anti-lung, liver, kidney, heart, and peritoneal fibrosis|
|Applications||Pharmaceutical raw materials|
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis . Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
White crystal powder
Loss on drying
Known single impurity
Unknown single impurity
In Europe, pirfenidone is indicated for the treatment of mild-to-moderate idiopathic pulmonary fibrosis. It was approved by the European Medicines Agency (EMA) in 2011. In October 2008, it was approved for use in Japan, in India in 2010, and in China in 2011 (commercial launch in 2014). In October 2014, it was approved for sale in the United States.
In Mexico it has been approved on a gel form for the treatment of scars and fibrotic tissue and has proven to be effective in the treatment of skin ulcers, such as diabetic foot.
Packaging & Delivery
1. Professional team for package and shipment.Special way to ship 100grams to 100kg powders at one time to your country
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4. Many kinds of shipment, also can be as your requirement.
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